Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Monomerid = 50198939
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198939((R)-1-butyl-3-((R)-1-hydroxy-2-methyl-propyl)-9-(4...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198939((R)-1-butyl-3-((R)-1-hydroxy-2-methyl-propyl)-9-(4...)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198939((R)-1-butyl-3-((R)-1-hydroxy-2-methyl-propyl)-9-(4...)
Affinity DataIC50:  84nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1alpha-induced calcium mobilization Ca assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198939((R)-1-butyl-3-((R)-1-hydroxy-2-methyl-propyl)-9-(4...)
Affinity DataIC50:  229nMAssay Description:Antagonist activity at human CCR5 expressed in HOS cells assessed as inhibition of cell fusion with HIV gp120 expressing HEK293 cells by LTR lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed