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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50202125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50202125
PNG
(CHEMBL247548 | N-(4-bromo-2-((4,5-dimethyl-1,3-dio...)
Show SMILES Cc1ccc2C(=O)N(Cc3cc(Br)ccc3NC(=O)c3ccccn3)C(=O)c2c1C
Show InChI InChI=1S/C23H18BrN3O3/c1-13-6-8-17-20(14(13)2)23(30)27(22(17)29)12-15-11-16(24)7-9-18(15)26-21(28)19-5-3-4-10-25-19/h3-11H,12H2,1-2H3,(H,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Merck& Co.

Curated by ChEMBL


Assay Description
Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assay


Bioorg Med Chem Lett 17: 1386-91 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.081
BindingDB Entry DOI: 10.7270/Q22V2GXH
More data for this
Ligand-Target Pair