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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50202136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50202136
PNG
(CHEMBL246935 | N-(4-bromo-2-((5-fluoro-1,3-dioxois...)
Show SMILES Fc1ccc2C(=O)N(Cc3cc(Br)ccc3NC(=O)c3ccccn3)C(=O)c2c1
Show InChI InChI=1S/C21H13BrFN3O3/c22-13-4-7-17(25-19(27)18-3-1-2-8-24-18)12(9-13)11-26-20(28)15-6-5-14(23)10-16(15)21(26)29/h1-10H,11H2,(H,25,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 930n/an/an/an/a



Merck& Co.

Curated by ChEMBL


Assay Description
Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assay


Bioorg Med Chem Lett 17: 1386-91 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.081
BindingDB Entry DOI: 10.7270/Q22V2GXH
More data for this
Ligand-Target Pair