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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50203572   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50203572
PNG
((1-(4-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES OCC1(CCCC1)N1CCN(CC1)C1CCc2ccc(OCc3noc(n3)-c3ccc(Cl)cc3)cc12
Show InChI InChI=1/C28H33ClN4O3/c29-22-7-3-21(4-8-22)27-30-26(31-36-27)18-35-23-9-5-20-6-10-25(24(20)17-23)32-13-15-33(16-14-32)28(19-34)11-1-2-12-28/h3-5,7-9,17,25,34H,1-2,6,10-16,18-19H2
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
27n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]NPTS from human GlyT1C expressed in HEK293 cells


Bioorg Med Chem Lett 17: 1675-8 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.109
BindingDB Entry DOI: 10.7270/Q25H7FXG
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50203572
PNG
((1-(4-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES OCC1(CCCC1)N1CCN(CC1)C1CCc2ccc(OCc3noc(n3)-c3ccc(Cl)cc3)cc12
Show InChI InChI=1/C28H33ClN4O3/c29-22-7-3-21(4-8-22)27-30-26(31-36-27)18-35-23-9-5-20-6-10-25(24(20)17-23)32-13-15-33(16-14-32)28(19-34)11-1-2-12-28/h3-5,7-9,17,25,34H,1-2,6,10-16,18-19H2
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity to GlyT1


Bioorg Med Chem Lett 19: 2974-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.035
BindingDB Entry DOI: 10.7270/Q2F76CKH
More data for this
Ligand-Target Pair