BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, inducible' and Monomerid = 50205949   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50205949
PNG
(CHEMBL220213 | N-(1,3-benzodioxol-5-ylmethyl)-1-[3...)
Show SMILES O=C(CC1CCCCN1c1cccc(c1)-n1ccnc1)NCc1ccc2OCOc2c1
Show InChI InChI=1/C24H26N4O3/c29-24(26-15-18-7-8-22-23(12-18)31-17-30-22)14-21-4-1-2-10-28(21)20-6-3-5-19(13-20)27-11-9-25-16-27/h3,5-9,11-13,16,21H,1-2,4,10,14-15,17H2,(H,26,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of cytokine-induced iNOS expressed in human A172 cells assessed as inhibition of NO formation


J Med Chem 50: 1146-57 (2007)


Article DOI: 10.1021/jm061319i
BindingDB Entry DOI: 10.7270/Q2SX6CWJ
More data for this
Ligand-Target Pair