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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50207078   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50207078
PNG
(4-(3,5-Difluorophenyl)-N-(6-methylpyrindin-2-yl)pi...)
Show SMILES Cc1cccc(NC(=O)c2cc(ccn2)-c2cc(F)cc(F)c2)n1
Show InChI InChI=1S/C18H13F2N3O/c1-11-3-2-4-17(22-11)23-18(24)16-9-12(5-6-21-16)13-7-14(19)10-15(20)8-13/h2-10H,1H3,(H,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Antagonist activity at mGluR5 expressed in CHO cells assessed as phosphoinositide hydrolysis


Bioorg Med Chem Lett 17: 2074-9 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.083
BindingDB Entry DOI: 10.7270/Q228078G
More data for this
Ligand-Target Pair