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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50207989   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50207989
PNG
(3-(1-(2-methoxybenzyl)-piperidin-4-yl)-5,5-dipheny...)
Show SMILES COc1ccccc1CN1CCC(CC1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-33-26-15-9-8-10-22(26)20-30-18-16-25(17-19-30)31-21-28(29-27(31)32,23-11-4-2-5-12-23)24-13-6-3-7-14-24/h2-15,25H,16-21H2,1H3,(H,29,32)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
83.7n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHO K1 cells


J Med Chem 50: 1571-83 (2007)


Article DOI: 10.1021/jm061159a
BindingDB Entry DOI: 10.7270/Q2QV3M61
More data for this
Ligand-Target Pair