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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50207991   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50207991
PNG
(3-(1-(3-pyridylmethyl)-piperidin-4-yl)-5,5-dipheny...)
Show SMILES O=C1NC(CN1C1CCN(Cc2cccnc2)CC1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H28N4O/c31-25-28-26(22-9-3-1-4-10-22,23-11-5-2-6-12-23)20-30(25)24-13-16-29(17-14-24)19-21-8-7-15-27-18-21/h1-12,15,18,24H,13-14,16-17,19-20H2,(H,28,31)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
1.13E+3n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHO K1 cells


J Med Chem 50: 1571-83 (2007)


Article DOI: 10.1021/jm061159a
BindingDB Entry DOI: 10.7270/Q2QV3M61
More data for this
Ligand-Target Pair