Found 6 Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50209245 TargetNitric oxide synthase, endothelial(Rattus norvegicus)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.89E+3nMAssay Description:Inhibitory activity against human endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by endothelial NOS from human umbilical vein endothelial cells.More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...More data for this Ligand-Target Pair
