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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50209331   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50209331
PNG
(1-(6-(azepan-1-yl)-2-cyclopropyl-5-methylpyrimidin...)
Show SMILES Cc1c(nc(nc1N1CCCCCC1)C1CC1)N1CC(C1)C#N
Show InChI InChI=1S/C18H25N5/c1-13-17(22-8-4-2-3-5-9-22)20-16(15-6-7-15)21-18(13)23-11-14(10-19)12-23/h14-15H,2-9,11-12H2,1H3
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Similars

Article
PubMed
794n/an/an/an/an/an/an/an/a



UCB Pharma SA

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylscopolamine from human recombinant M3 muscarinic receptor expressed in CHO cell membrane


Bioorg Med Chem Lett 17: 3077-80 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.047
BindingDB Entry DOI: 10.7270/Q2PR7VNX
More data for this
Ligand-Target Pair