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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor I receptor' and Monomerid = 50209385   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50209385
PNG
(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)
Show SMILES CC1CNC(=N1)c1cc(C)c2nc([nH]c2c1)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O
Show InChI InChI=1S/C25H25ClN6O2/c1-13-8-16(23-29-11-14(2)30-23)10-19-22(13)32-24(31-19)21-18(6-7-27-25(21)34)28-12-20(33)15-4-3-5-17(26)9-15/h3-10,14,20,33H,11-12H2,1-2H3,(H,29,30)(H,31,32)(H2,27,28,34)
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Similars

Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human IGF1R expressed in recombinant insect cells


Bioorg Med Chem Lett 17: 3072-6 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.048
BindingDB Entry DOI: 10.7270/Q2F76C71
More data for this
Ligand-Target Pair