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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50212327   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50212327
PNG
(3-(amino(carboxy)(9H-thioxanthen-9-yl)methyl)cyclo...)
Show SMILES NC(C1CC(C1)C(O)=O)(C1c2ccccc2Sc2ccccc12)C(O)=O
Show InChI InChI=1/C20H19NO4S/c21-20(19(24)25,12-9-11(10-12)18(22)23)17-13-5-1-3-7-15(13)26-16-8-4-2-6-14(16)17/h1-8,11-12,17H,9-10,21H2,(H,22,23)(H,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Lilly Research Labs

Curated by ChEMBL


Assay Description
Antagonist activity at mGlu1 receptor


J Med Chem 50: 2563-8 (2007)


Article DOI: 10.1021/jm060950g
BindingDB Entry DOI: 10.7270/Q2XS5W7Q
More data for this
Ligand-Target Pair