BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclooxygenase-2' and Monomerid = 50213229   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50213229
PNG
(CHEMBL229738 | O2-acetoxymethyl 1-{N-[2-(2-(1-(4-c...)
Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCCN(C)[N+](\[O-])=N\OCOC(C)=O)c2c1
Show InChI InChI=1S/C25H27ClN4O8/c1-16-21(14-24(32)36-12-11-28(3)30(34)27-38-15-37-17(2)31)22-13-20(35-4)9-10-23(22)29(16)25(33)18-5-7-19(26)8-6-18/h5-10,13H,11-12,14-15H2,1-4H3/b30-27-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National Cancer Institute at Frederick

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 15: 4767-74 (2007)


Article DOI: 10.1016/j.bmc.2007.05.009
BindingDB Entry DOI: 10.7270/Q23B5ZT7
More data for this
Ligand-Target Pair