Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Monomerid = 50213655
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50213655((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(tetrahydro-...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50213655((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(tetrahydro-...)
Affinity DataIC50:  205nMAssay Description:Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50213655((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(tetrahydro-...)
Affinity DataIC50:  480nMAssay Description:Inhibition of GnRHR in rat pituitary cells assessed as inhibition of GnRH-stimulated LH releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed