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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50214069   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50214069
PNG
(5-(4-chlorophenyl)-6-methyl-1-(pyrimidin-5-yl)-1H-...)
Show SMILES Cc1nc2n(ncc2c(=O)n1-c1ccc(Cl)cc1)-c1cncnc1
Show InChI InChI=1S/C16H11ClN6O/c1-10-21-15-14(8-20-23(15)13-6-18-9-19-7-13)16(24)22(10)12-4-2-11(17)3-5-12/h2-9H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.80E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR1 receptor expressed in 132N1 cells assessed as inhibition of glutamate-induced calcium flux by FLIPR assay


Bioorg Med Chem Lett 17: 4303-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.028
BindingDB Entry DOI: 10.7270/Q2445M5T
More data for this
Ligand-Target Pair