BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50218000   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50218000
PNG
(CHEMBL251150 | {[2-(2''-fluoro-[1,1';3',1'']terphe...)
Show SMILES CN(CCOc1ccc(cc1-c1ccccc1F)-c1ccccc1)CC(O)=O
Show InChI InChI=1S/C23H22FNO3/c1-25(16-23(26)27)13-14-28-22-12-11-18(17-7-3-2-4-8-17)15-20(22)19-9-5-6-10-21(19)24/h2-12,15H,13-14,16H2,1H3,(H,26,27)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 108n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cells


Bioorg Med Chem Lett 17: 5233-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.074
BindingDB Entry DOI: 10.7270/Q28915K8
More data for this
Ligand-Target Pair