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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50218003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50218003
PNG
((methyl-{2-[3'-methyl-3-(thiophene-2-carbonyl)-bip...)
Show SMILES CN(CCOc1ccc(cc1C(=O)c1cccs1)-c1cccc(C)c1)CC(O)=O
Show InChI InChI=1S/C23H23NO4S/c1-16-5-3-6-17(13-16)18-8-9-20(28-11-10-24(2)15-22(25)26)19(14-18)23(27)21-7-4-12-29-21/h3-9,12-14H,10-11,15H2,1-2H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cells


Bioorg Med Chem Lett 17: 5233-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.074
BindingDB Entry DOI: 10.7270/Q28915K8
More data for this
Ligand-Target Pair