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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50218004   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50218004
PNG
(({2-[4'-methoxy-3'-methyl-3-(thiophene-2-carbonyl)...)
Show SMILES COc1ccc(cc1C)-c1ccc(OCCN(C)CC(O)=O)c(c1)C(=O)c1cccs1
Show InChI InChI=1S/C24H25NO5S/c1-16-13-17(6-8-20(16)29-3)18-7-9-21(30-11-10-25(2)15-23(26)27)19(14-18)24(28)22-5-4-12-31-22/h4-9,12-14H,10-11,15H2,1-3H3,(H,26,27)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cells


Bioorg Med Chem Lett 17: 5233-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.074
BindingDB Entry DOI: 10.7270/Q28915K8
More data for this
Ligand-Target Pair