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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50218016   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50218016
PNG
(({2-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-thiop...)
Show SMILES CN(CCOc1ccc(cc1-c1cccs1)-c1ccc2OCCOc2c1)CC(O)=O
Show InChI InChI=1S/C23H23NO5S/c1-24(15-23(25)26)8-9-27-19-6-4-16(13-18(19)22-3-2-12-30-22)17-5-7-20-21(14-17)29-11-10-28-20/h2-7,12-14H,8-11,15H2,1H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cells


Bioorg Med Chem Lett 17: 5233-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.074
BindingDB Entry DOI: 10.7270/Q28915K8
More data for this
Ligand-Target Pair