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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50218024   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50218024
PNG
(CHEMBL399983 | {[2-(3-cyclohexylmethyl-biphenyl-4-...)
Show SMILES CN(CCOc1ccc(cc1CC1CCCCC1)-c1ccccc1)CC(O)=O
Show InChI InChI=1S/C24H31NO3/c1-25(18-24(26)27)14-15-28-23-13-12-21(20-10-6-3-7-11-20)17-22(23)16-19-8-4-2-5-9-19/h3,6-7,10-13,17,19H,2,4-5,8-9,14-16,18H2,1H3,(H,26,27)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 289n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cells


Bioorg Med Chem Lett 17: 5233-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.074
BindingDB Entry DOI: 10.7270/Q28915K8
More data for this
Ligand-Target Pair