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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50223960   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50223960
PNG
(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl phenyl(thi...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)N(Cc1ccsc1)c1ccccc1
Show InChI InChI=1S/C20H24N2O2S/c1-21-17-7-8-18(21)12-19(11-17)24-20(23)22(13-15-9-10-25-14-15)16-5-3-2-4-6-16/h2-6,9-10,14,17-19H,7-8,11-13H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 27.5n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilization


Bioorg Med Chem Lett 17: 6066-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.071
BindingDB Entry DOI: 10.7270/Q2BC3Z8T
More data for this
Ligand-Target Pair