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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Monomerid = 50223967   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50223967
PNG
(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 2-bromoben...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)N(Cc1ccccc1Br)c1ccccc1
Show InChI InChI=1S/C22H25BrN2O2/c1-24-18-11-12-19(24)14-20(13-18)27-22(26)25(17-8-3-2-4-9-17)15-16-7-5-6-10-21(16)23/h2-10,18-20H,11-15H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.39E+3n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilization


Bioorg Med Chem Lett 17: 6066-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.071
BindingDB Entry DOI: 10.7270/Q2BC3Z8T
More data for this
Ligand-Target Pair