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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Monomerid = 50223969   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50223969
PNG
(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-cyanoben...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)N(Cc1ccc(cc1)C#N)c1ccsc1
Show InChI InChI=1S/C21H23N3O2S/c1-23-17-6-7-18(23)11-20(10-17)26-21(25)24(19-8-9-27-14-19)13-16-4-2-15(12-22)3-5-16/h2-5,8-9,14,17-18,20H,6-7,10-11,13H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 363n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilization


Bioorg Med Chem Lett 17: 6066-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.071
BindingDB Entry DOI: 10.7270/Q2BC3Z8T
More data for this
Ligand-Target Pair