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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50223972   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50223972
PNG
(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-cyanoben...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)N(Cc1ccc(cc1)C#N)c1ccccc1
Show InChI InChI=1S/C23H25N3O2/c1-25-20-11-12-21(25)14-22(13-20)28-23(27)26(19-5-3-2-4-6-19)16-18-9-7-17(15-24)8-10-18/h2-10,20-22H,11-14,16H2,1H3
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KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.16E+3n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilization


Bioorg Med Chem Lett 17: 6066-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.071
BindingDB Entry DOI: 10.7270/Q2BC3Z8T
More data for this
Ligand-Target Pair