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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50223975   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50223975
PNG
(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 3-methoxyb...)
Show SMILES COc1cccc(CN(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2)c1
Show InChI InChI=1S/C23H28N2O3/c1-24-19-11-12-20(24)15-22(14-19)28-23(26)25(18-8-4-3-5-9-18)16-17-7-6-10-21(13-17)27-2/h3-10,13,19-20,22H,11-12,14-16H2,1-2H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 2.14E+3n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilization


Bioorg Med Chem Lett 17: 6066-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.071
BindingDB Entry DOI: 10.7270/Q2BC3Z8T
More data for this
Ligand-Target Pair