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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Monomerid = 50223979   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50223979
PNG
(3-[(4-cyano-benzyl)-phenyl-carbamoyloxy]-8,8-dimet...)
Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)N(Cc1ccc(cc1)C#N)c1ccccc1
Show InChI InChI=1S/C24H28N3O2/c1-27(2)21-12-13-22(27)15-23(14-21)29-24(28)26(20-6-4-3-5-7-20)17-19-10-8-18(16-25)9-11-19/h3-11,21-23H,12-15,17H2,1-2H3/q+1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 258n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilization


Bioorg Med Chem Lett 17: 6066-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.071
BindingDB Entry DOI: 10.7270/Q2BC3Z8T
More data for this
Ligand-Target Pair