Found 2 Enz. Inhib. hit(s) with Target = 'ATP-Binding Cassette Transporter ABCG2' and Monomerid = 50226181
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hospital For Sick Children
Curated by ChEMBL
Hospital For Sick Children
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of mitoxantrone efflux in BCRP-expressing MCF7-MX cellsMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hospital For Sick Children
Curated by ChEMBL
Hospital For Sick Children
Curated by ChEMBL
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed human PC-6/SN2-5 cells membrane vesicle mediated topotecan transport by HPLC analysisMore data for this Ligand-Target Pair