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Found 2 Enz. Inhib. hit(s) with Target = 'ATP-Binding Cassette Transporter ABCG2' and Monomerid = 50226181
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hospital For Sick Children

Curated by ChEMBL
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  2.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of mitoxantrone efflux in BCRP-expressing MCF7-MX cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hospital For Sick Children

Curated by ChEMBL
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  2.68E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed human PC-6/SN2-5 cells membrane vesicle mediated topotecan transport by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank