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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Monomerid = 50228363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50228363
PNG
(CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...)
Show SMILES O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1
Show InChI InChI=1S/C25H23N7OS/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31/h1-8,13,15-16,26H,9-12,14H2,(H,29,33)
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Article
PubMed
n/an/a 6.28E+3n/an/an/an/an/an/a



Sirtris Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of muscarinic M2 receptor


J Med Chem 52: 1275-83 (2010)


Article DOI: 10.1021/jm8012954
BindingDB Entry DOI: 10.7270/Q2ZC82V5
More data for this
Ligand-Target Pair