Found 4 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50231755 TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute
Curated by ChEMBL
Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Modulation of mGluR5 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Brain Science Institute
Curated by ChEMBL
Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
