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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50235540   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50235540
PNG
(2,6-difluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methy...)
Show SMILES CN1CCN(CCOc2cn3ncnc(Oc4ccc(NC(=O)c5c(F)cccc5F)cc4F)c3c2C)CC1
Show InChI InChI=1S/C27H27F3N6O3/c1-17-23(38-13-12-35-10-8-34(2)9-11-35)15-36-25(17)27(31-16-32-36)39-22-7-6-18(14-21(22)30)33-26(37)24-19(28)4-3-5-20(24)29/h3-7,14-16H,8-13H2,1-2H3,(H,33,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50235540
PNG
(2,6-difluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methy...)
Show SMILES CN1CCN(CCOc2cn3ncnc(Oc4ccc(NC(=O)c5c(F)cccc5F)cc4F)c3c2C)CC1
Show InChI InChI=1S/C27H27F3N6O3/c1-17-23(38-13-12-35-10-8-34(2)9-11-35)15-36-25(17)27(31-16-32-36)39-22-7-6-18(14-21(22)30)33-26(37)24-19(28)4-3-5-20(24)29/h3-7,14-16H,8-13H2,1-2H3,(H,33,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system


Bioorg Med Chem Lett 18: 1945-51 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.121
BindingDB Entry DOI: 10.7270/Q2125SFV
More data for this
Ligand-Target Pair