BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50235570   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50235570
PNG
(1-(3-fluoro-4-(5-(piperazin-1-ylmethyl)pyrrolo[1,2...)
Show SMILES Fc1ccc(CC(=O)NC(=O)Nc2ccc(Oc3ncnn4ccc(CN5CCNCC5)c34)c(F)c2)cc1
Show InChI InChI=1S/C26H25F2N7O3/c27-19-3-1-17(2-4-19)13-23(36)33-26(37)32-20-5-6-22(21(28)14-20)38-25-24-18(7-10-35(24)31-16-30-25)15-34-11-8-29-9-12-34/h1-7,10,14,16,29H,8-9,11-13,15H2,(H2,32,33,36,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50235570
PNG
(1-(3-fluoro-4-(5-(piperazin-1-ylmethyl)pyrrolo[1,2...)
Show SMILES Fc1ccc(CC(=O)NC(=O)Nc2ccc(Oc3ncnn4ccc(CN5CCNCC5)c34)c(F)c2)cc1
Show InChI InChI=1S/C26H25F2N7O3/c27-19-3-1-17(2-4-19)13-23(36)33-26(37)32-20-5-6-22(21(28)14-20)38-25-24-18(7-10-35(24)31-16-30-25)15-34-11-8-29-9-12-34/h1-7,10,14,16,29H,8-9,11-13,15H2,(H2,32,33,36,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system


Bioorg Med Chem Lett 18: 1945-51 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.121
BindingDB Entry DOI: 10.7270/Q2125SFV
More data for this
Ligand-Target Pair