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Found 3 Enz. Inhib. hit(s) with Target = 'ATP-Binding Cassette Transporter ABCG2' and Monomerid = 50241467
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50241467(CHEMBL555611 | N-(4-(2-(6,7-dimethoxy-3,4-dihydroi...)
Affinity DataIC50:  4.38E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells by pheophorbide A assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50241467(CHEMBL555611 | N-(4-(2-(6,7-dimethoxy-3,4-dihydroi...)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells by pheophorbide A assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50241467(CHEMBL555611 | N-(4-(2-(6,7-dimethoxy-3,4-dihydroi...)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed