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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-3 Adrenergic Receptor' and Monomerid = 50243224   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50243224
PNG
(3-Ethoxy-4-[(2R)-2-{[(2R)-2-hydroxy-2-phenylethyl]...)
Show SMILES CCOc1cc(ccc1C(O)=O)-c1ccc(C[C@@H](C)NC[C@H](O)c2ccccc2)cc1
Show InChI InChI=1/C26H29NO4/c1-3-31-25-16-22(13-14-23(25)26(29)30)20-11-9-19(10-12-20)15-18(2)27-17-24(28)21-7-5-4-6-8-21/h4-14,16,18,24,27-28H,3,15,17H2,1-2H3,(H,29,30)/t18-,24+/s2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.310n/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay


J Med Chem 51: 4002-20 (2008)


Article DOI: 10.1021/jm8000345
BindingDB Entry DOI: 10.7270/Q2MS3SKD
More data for this
Ligand-Target Pair