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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50243543   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50243543
PNG
(4-[(2-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]ami...)
Show SMILES CCCOc1cc(ccc1C(O)=O)-c1ccc(NCCNC[C@H](O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C26H29ClN2O4/c1-2-14-33-25-16-19(8-11-23(25)26(31)32)18-6-9-22(10-7-18)29-13-12-28-17-24(30)20-4-3-5-21(27)15-20/h3-11,15-16,24,28-30H,2,12-14,17H2,1H3,(H,31,32)/t24-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 11n/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay


J Med Chem 51: 4002-20 (2008)


Article DOI: 10.1021/jm8000345
BindingDB Entry DOI: 10.7270/Q2MS3SKD
More data for this
Ligand-Target Pair