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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50245394   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50245394
PNG
(CHEMBL461120 | N-[({5-[(6,7-Dimethoxyquinolin-4-yl...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)CN4CCCCC4)nc3)c2cc1OC
Show InChI InChI=1S/C24H27N5O5/c1-32-20-12-17-18(13-21(20)33-2)25-9-8-19(17)34-16-6-7-22(26-14-16)27-24(31)28-23(30)15-29-10-4-3-5-11-29/h6-9,12-14H,3-5,10-11,15H2,1-2H3,(H2,26,27,28,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
500n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human activated c-Met by PK/LDH coupled kinetic assay


Eur J Med Chem 43: 1321-9 (2008)


Article DOI: 10.1016/j.ejmech.2007.08.011
BindingDB Entry DOI: 10.7270/Q2HX1CGS
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50245394
PNG
(CHEMBL461120 | N-[({5-[(6,7-Dimethoxyquinolin-4-yl...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)CN4CCCCC4)nc3)c2cc1OC
Show InChI InChI=1S/C24H27N5O5/c1-32-20-12-17-18(13-21(20)33-2)25-9-8-19(17)34-16-6-7-22(26-14-16)27-24(31)28-23(30)15-29-10-4-3-5-11-29/h6-9,12-14H,3-5,10-11,15H2,1-2H3,(H2,26,27,28,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair