BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Monomerid = 50245964   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50245964
PNG
((1S,2R)-1-(4-fluoro-2-methylphenoxy)-2-((methylami...)
Show SMILES CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccc(F)cc1C
Show InChI InChI=1/C18H20FNO2/c1-12-9-14(19)7-8-16(12)22-17-15-6-4-3-5-13(15)10-18(17,21)11-20-2/h3-9,17,20-21H,10-11H2,1-2H3/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6 (unknown origin)


Bioorg Med Chem Lett 18: 6151-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.013
BindingDB Entry DOI: 10.7270/Q2JS9Q86
More data for this
Ligand-Target Pair