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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50246818   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50246818
PNG
(1,3-Bis(3-(4-(4-(pyrrolidin-1-yl)butanamido)phenyl...)
Show SMILES O=C(CCCN1CCCC1)Nc1ccc(NC(=O)c2cccc(NC(=O)Nc3cccc(c3)C(=O)Nc3ccc(NC(=O)CCCN4CCCC4)cc3)c2)cc1
Show InChI InChI=1S/C43H50N8O5/c52-39(13-7-27-50-23-1-2-24-50)44-33-15-19-35(20-16-33)46-41(54)31-9-5-11-37(29-31)48-43(56)49-38-12-6-10-32(30-38)42(55)47-36-21-17-34(18-22-36)45-40(53)14-8-28-51-25-3-4-26-51/h5-6,9-12,15-22,29-30H,1-4,7-8,13-14,23-28H2,(H,44,52)(H,45,53)(H,46,54)(H,47,55)(H2,48,49,56)
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PC cid
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Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



University of London

Curated by ChEMBL


Assay Description
Inhibition of telomerase (unknown origin) by TRAP-LIG assay


J Med Chem 51: 7751-67 (2008)


Article DOI: 10.1021/jm801245v
BindingDB Entry DOI: 10.7270/Q2CN73SS
More data for this
Ligand-Target Pair