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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50250921   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50250921
PNG
(CHEMBL518103 | isaindigotone)
Show SMILES COc1cc(\C=C2/CCn3c2nc2ccccc2c3=O)cc(OC)c1O
Show InChI InChI=1S/C20H18N2O4/c1-25-16-10-12(11-17(26-2)18(16)23)9-13-7-8-22-19(13)21-15-6-4-3-5-14(15)20(22)24/h3-6,9-11,23H,7-8H2,1-2H3/b13-9+
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Universidad de Murcia

Curated by ChEMBL


Assay Description
Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIA


J Nat Prod 64: 1297-300 (2001)


Article DOI: 10.1021/np0101898
BindingDB Entry DOI: 10.7270/Q2GT5MXP
More data for this
Ligand-Target Pair