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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50250946   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50250946
PNG
(3-(4'-Acetoxy-3',5'-dimethoxy)benzylidene-1,2-dihy...)
Show SMILES COc1cc(\C=C2/CCn3c2nc2ccccc2c3=O)cc(OC)c1OC(C)=O
Show InChI InChI=1S/C22H20N2O5/c1-13(25)29-20-18(27-2)11-14(12-19(20)28-3)10-15-8-9-24-21(15)23-17-7-5-4-6-16(17)22(24)26/h4-7,10-12H,8-9H2,1-3H3/b15-10+
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PC sid
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Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Universidad de Murcia

Curated by ChEMBL


Assay Description
Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIA


J Nat Prod 64: 1297-300 (2001)


Article DOI: 10.1021/np0101898
BindingDB Entry DOI: 10.7270/Q2GT5MXP
More data for this
Ligand-Target Pair