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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin L' and Monomerid = 50252653   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin L1


(Homo sapiens (Human))
BDBM50252653
PNG
(7-(2-cyclohexylethyl)-6-((methyl(phenyl)amino)meth...)
Show SMILES CN(Cc1cc2cnc(nc2n1CCC1CCCCC1)C#N)c1ccccc1
Show InChI InChI=1S/C23H27N5/c1-27(20-10-6-3-7-11-20)17-21-14-19-16-25-22(15-24)26-23(19)28(21)13-12-18-8-4-2-5-9-18/h3,6-7,10-11,14,16,18H,2,4-5,8-9,12-13,17H2,1H3
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Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay


Bioorg Med Chem Lett 18: 3959-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.009
BindingDB Entry DOI: 10.7270/Q23N235B
More data for this
Ligand-Target Pair