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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, AMPA 2' and Monomerid = 50252918   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, AMPA 2


(Rattus norvegicus)
BDBM50252918
PNG
((S)-1-(3'-Amino-3'-carboxypropyl)-6,7-dihydro-1H-c...)
Show SMILES N[C@@H](CCn1c2CCCc2c(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C11H15N3O4/c12-7(10(16)17)4-5-14-8-3-1-2-6(8)9(15)13-11(14)18/h7H,1-5,12H2,(H,16,17)(H,13,15,18)/t7-/m0/s1
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MMDB

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Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



European Research Centre for Drug Discovery and Development (NatSynDrugs)

Curated by ChEMBL


Assay Description
Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cells


J Med Chem 51: 6614-8 (2008)


Article DOI: 10.1021/jm800865a
BindingDB Entry DOI: 10.7270/Q261117R
More data for this
Ligand-Target Pair