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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50253651   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50253651
PNG
(CHEMBL510879 | S)-2-Amino-4-methyl-pentanoic acid ...)
Show SMILES CC(C)C[C@H](N)C(=O)NCC(=O)Nc1ccc2C(=O)c3cc(NC(=O)CNC(=O)[C@@H](N)CC(C)C)ccc3C(=O)c2c1
Show InChI InChI=1S/C30H38N6O6/c1-15(2)9-23(31)29(41)33-13-25(37)35-17-5-7-19-21(11-17)27(39)20-8-6-18(12-22(20)28(19)40)36-26(38)14-34-30(42)24(32)10-16(3)4/h5-8,11-12,15-16,23-24H,9-10,13-14,31-32H2,1-4H3,(H,33,41)(H,34,42)(H,35,37)(H,36,38)/t23-,24-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a>4.00E+4n/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human JR8 cells by TRAP assay


J Med Chem 51: 5566-74 (2008)


Article DOI: 10.1021/jm800160v
BindingDB Entry DOI: 10.7270/Q2R78F1Q
More data for this
Ligand-Target Pair