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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50253687   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50253687
PNG
((S)-2-Amino-N-(2-{6-[3-((S)-2-amino-3-phenyl-propi...)
Show SMILES N[C@@H](Cc1ccccc1)C(=O)NCCC(=O)Nc1ccc2C(=O)c3cc(NC(=O)CCNC(=O)[C@@H](N)Cc4ccccc4)ccc3C(=O)c2c1
Show InChI InChI=1S/C38H38N6O6/c39-31(19-23-7-3-1-4-8-23)37(49)41-17-15-33(45)43-25-11-13-27-29(21-25)35(47)28-14-12-26(22-30(28)36(27)48)44-34(46)16-18-42-38(50)32(40)20-24-9-5-2-6-10-24/h1-14,21-22,31-32H,15-20,39-40H2,(H,41,49)(H,42,50)(H,43,45)(H,44,46)/t31-,32-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a>4.00E+4n/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human JR8 cells by TRAP assay


J Med Chem 51: 5566-74 (2008)


Article DOI: 10.1021/jm800160v
BindingDB Entry DOI: 10.7270/Q2R78F1Q
More data for this
Ligand-Target Pair