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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50253719   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50253719
PNG
((S)-2-Amino-N-(2-{7-[3-((S)-2-amino-propionylamino...)
Show SMILES C[C@H](N)C(=O)NCCC(=O)Nc1ccc2C(=O)c3ccc(NC(=O)CCNC(=O)[C@H](C)N)cc3C(=O)c2c1
Show InChI InChI=1S/C26H30N6O6/c1-13(27)25(37)29-9-7-21(33)31-15-3-5-17-19(11-15)24(36)20-12-16(4-6-18(20)23(17)35)32-22(34)8-10-30-26(38)14(2)28/h3-6,11-14H,7-10,27-28H2,1-2H3,(H,29,37)(H,30,38)(H,31,33)(H,32,34)/t13-,14-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a 1.50E+4n/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human JR8 cells by TRAP assay


J Med Chem 51: 5566-74 (2008)


Article DOI: 10.1021/jm800160v
BindingDB Entry DOI: 10.7270/Q2R78F1Q
More data for this
Ligand-Target Pair