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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50253730   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50253730
PNG
(9,10-Dioxo-9,10-dihydro-anthracene-2,6-dicarboxyli...)
Show SMILES CC(C)C[C@H](N)C(=O)NCCNC(=O)c1ccc2C(=O)c3cc(ccc3C(=O)c2c1)C(=O)NCCNC(=O)[C@@H](N)CC(C)C
Show InChI InChI=1S/C32H42N6O6/c1-17(2)13-25(33)31(43)37-11-9-35-29(41)19-5-7-21-23(15-19)27(39)22-8-6-20(16-24(22)28(21)40)30(42)36-10-12-38-32(44)26(34)14-18(3)4/h5-8,15-18,25-26H,9-14,33-34H2,1-4H3,(H,35,41)(H,36,42)(H,37,43)(H,38,44)/t25-,26-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a>4.00E+4n/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human JR8 cells by TRAP assay


J Med Chem 51: 5566-74 (2008)


Article DOI: 10.1021/jm800160v
BindingDB Entry DOI: 10.7270/Q2R78F1Q
More data for this
Ligand-Target Pair