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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50253786   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50253786
PNG
(9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxyli...)
Show SMILES N[C@@H](CCCN=C(N)N)C(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)[C@@H](N)CCCN=C(N)N
Show InChI InChI=1S/C32H44N12O6/c33-23(3-1-9-43-31(35)36)29(49)41-13-11-39-27(47)17-5-7-19-21(15-17)26(46)22-16-18(6-8-20(22)25(19)45)28(48)40-12-14-42-30(50)24(34)4-2-10-44-32(37)38/h5-8,15-16,23-24H,1-4,9-14,33-34H2,(H,39,47)(H,40,48)(H,41,49)(H,42,50)(H4,35,36,43)(H4,37,38,44)/t23-,24-/m0/s1
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PC cid
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Similars

Article
PubMed
n/an/an/an/a 1.20E+3n/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human JR8 cells by TRAP assay


J Med Chem 51: 5566-74 (2008)


Article DOI: 10.1021/jm800160v
BindingDB Entry DOI: 10.7270/Q2R78F1Q
More data for this
Ligand-Target Pair