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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50257534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257534
PNG
(3-(4-fluorophenyl)-2-(pyrimidin-5-yl)-1H-pyrrolo[3...)
Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1cncnc1
Show InChI InChI=1S/C18H10FN5/c19-13-3-1-11(2-4-13)16-17(12-8-21-10-22-9-12)24-15-6-5-14(7-20)23-18(15)16/h1-6,8-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257534
PNG
(3-(4-fluorophenyl)-2-(pyrimidin-5-yl)-1H-pyrrolo[3...)
Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1cncnc1
Show InChI InChI=1S/C18H10FN5/c19-13-3-1-11(2-4-13)16-17(12-8-21-10-22-9-12)24-15-6-5-14(7-20)23-18(15)16/h1-6,8-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair