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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50257585   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257585
PNG
(2-(6-aminopyridin-3-yl)-3-(3-chloro-4-fluorophenyl...)
Show SMILES Nc1ccc(cn1)-c1[nH]c2ccc(nc2c1-c1ccc(F)c(Cl)c1)C#N
Show InChI InChI=1S/C19H11ClFN5/c20-13-7-10(1-4-14(13)21)17-18(11-2-6-16(23)24-9-11)26-15-5-3-12(8-22)25-19(15)17/h1-7,9,26H,(H2,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair