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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50258615   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50258615
PNG
(4-(3'-Cyano-phenyl)-N-(6-methylpyridin-2-yl)-benza...)
Show SMILES Cc1cccc(NC(=O)c2ccc(cc2)-c2cccc(c2)C#N)n1
Show InChI InChI=1S/C20H15N3O/c1-14-4-2-7-19(22-14)23-20(24)17-10-8-16(9-11-17)18-6-3-5-15(12-18)13-21/h2-12H,1H3,(H,22,23,24)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [3H]MPEP from cloned mGluR5 (unknown origin) expressed in HEK293T cells by scintillation counting


J Med Chem 52: 3563-75 (2009)


Article DOI: 10.1021/jm900172f
BindingDB Entry DOI: 10.7270/Q2K937FV
More data for this
Ligand-Target Pair