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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase LCK' and Monomerid = 50263349
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263349(1-(6-aminopyrimidin-4-yl)-N-mesityl-1H-benzo[d]imi...)
Affinity DataIC50:  583nMAssay Description:Inhibition of TEL fused Lck (unknown origin)-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263349(1-(6-aminopyrimidin-4-yl)-N-mesityl-1H-benzo[d]imi...)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed